Corneal Collagen Cross-Linking

The cornea is the clear, dome-shaped surface of the eye. It is primarily made of microscopic fibers called collagen. The cornea’s main purpose is to bend (refract) incoming light to focus it onto the retina, the back part of the eye that receives and transmits vision information to the brain.

To provide clear vision, the cornea must have a smooth, regular curvature. Some corneal diseases, such as keratoconus, can cause the cornea to bulge into an irregular shape. This causes blurry vision and light sensitivity.

Corneal cross-linking, a groundbreaking procedure performed by Dr. Jesse Vislisel at Associated Eye Care, can stop the progression of these corneal diseases and eliminate the need for major surgery such as corneal transplantation. Dr. Vislisel is a board-certified ophthalmologist and cornea specialist in Stillwater, MN.

Vision For A Lifetime.

Call to schedule your appointment
(651) 275.3000

What is Corneal Cross-Linking?

Corneal collagen cross-linking, or CXL, is a procedure that strengthens the cornea to stabilize diseases that cause the cornea to form an irregular shape. Cross-linking is the first and only treatment available to prevent such eye conditions from worsening. The primary goal of the procedure is to prevent progression of the disease process, though many patients also experience improvement in corneal curvature and vision after recovery.

In some cases, the corneal shape can be significantly improved by combining CXL with topographically-guided photorefractive keratectomy (PRK). During this PRK procedure, pre-operative scans are used to plan a customized laser treatment aimed at improving the cornea’s shape to reduce glasses prescription and improve vision quality.

How Does Corneal Cross-Linking Work?

During the procedure, riboflavin (vitamin B2) drops are repeatedly placed in the eye and low-dose ultraviolet light is applied to the cornea. This causes a chemical reaction that thickens the natural collagen fibers in the cornea and forms additional bonds, or “cross-links,” between them. These changes strengthen and stabilize the cornea to prevent further distortion in shape. The treatment is extremely effective and stops disease progression in over 90% of cases.

View Video

Am I a Candidate for Corneal Cross-Linking?

Corneal cross-linking is typically recommended for patients with the following eye conditions that cause corneal thinning, weakening, and irregular corneal curvature:

Corneal cross-linking also kills harmful bacteria, fungi and other organisms. It is therefore also effective for treating corneal infections that are unresponsive to eye drops.Several factors are taken into consideration when determining whether CXL is a good treatment option:

The best way to determine your candidacy for corneal cross-linking is to talk to your eye doctor. A comprehensive examination and review of your symptoms will help your doctor recommend the best treatment for your eye condition.

What to Expect Before Your Procedure

Chart Illustrating a Weaker Cornea Compared to a Stronger One After Cornea Cross-Linking

Your doctor will schedule an evaluation to evaluate and discuss your condition. At this visit, you will undergo a detailed eye examination including vision assessment, corneal thickness (pachymetry) measurement, and mapping of the corneal shape (topography). This helps your doctor assess how to best treat your eyes.

What to Expect After Your Procedure

It is normal to experience discomfort, blurred vision, and sensitivity to light for days or weeks after your procedure. You will be prescribed anti-inflammatory eye drops to help reduce inflammation and antibiotic drops to prevent infection. Make sure to keep your eyes clean and avoid rubbing them after the procedure. If you experience pain that gets progressively worse, a sudden decrease in vision, or anything else out of the ordinary, contact your doctor immediately.

Several follow-up appointments will be required to ensure the cornea is healing properly. Once healing is complete, you may benefit from custom contact lenses to achieve the best vision possible. Your doctor will measure your vision over time and make a recommendation based on the results.

Corneal Cross-Linking, Stillwater, MN

Associated Eye Care offers treatment for cornea problems at our clinic on Curve Crest Boulevard in Stillwater. Corneal cross-linking consultations are scheduled with Dr. Vislisel at our Hugo, Stillwater, and Woodbury locations. Schedule an appointment now or call (800) 846-1877 for more information.

Visit one of our seven convenient locations

COVID-19 Important Safety Information: Learn More   |  Now Offering Telehealth Appointments: Learn More